Water is a source of life that circulates the globe and benefits humans and diverse ecosystems through interactions with the atmosphere, soil and other elements. Water shortage and pollution are causes of great concern for the future due to the continuing increase in the world population and economic expansion. Climate change is most likely to further deteriorate the situation. At Shionogi, we are acutely aware of the ramifications of water-related risks on the production of pharmaceutical products, as well as all aspects of our corporate life. Accordingly, we conduct careful risk assessment, taking appropriate measures based on the EHS policy to minimize risks.

[Risks and opportunities]

Quality water is an essential resource to manufacture pharmaceutical products. Considering the great impact on business continuity of possible depletion of water resources in the catchment areas where our plants are located, we used the internationally recognized WRI Aqueduct*1 and WWF Risk Filter*2 to assess water risks facing our major operating sites engaged in manufacturing and research. The risk items studied include those related to water supply necessary for its present operations and future business continuity, and the increase in the probability of occurrence of floods triggered by extreme meteorological phenomena attributable to climate change.
In-house deliberations based on the results of these studies, as well as past experience and knowledge, have concluded that water risks are relatively minor for the Shionogi Group at present and in the future. We have incorporated risk assessment based on the WRI Aqueduct into the selection of our suppliers to clarify their latent risks and prevent their development.
For future water-related risk assessment, we are considering consultation with experts. 
  1. ※1
    Water risk assessment tool developed and published by the WRI (World Resources Institute)
  2. ※2
    Water risk assessment tool developed and published by the WWF (World Wide Fund for Nature)

WRI Aqueduct Assessment Results (Baseline Water Stress)

Company Location No. of operating sites Risk level/no. of operating sites Future water
stress change
High High to
medium
Medium Medium
to low
Low
Shionogi Japan
(Iwate, Shiga, Osaka, Hyogo)
5 3 1 1 No major change up to 2040
Shionogi Pharma Chemicals Japan
(Tokushima)
1 1 No major change up to 2040
C&O Nanjing Plant China
(Jiangsu)
1 1 No major change up to 2040

WWF-Water Risk Filter Assessment (Baseline Water Stress)

Company Location No. of operating sites Risk level/no. of operating sites
High High to
medium
Medium Medium
to low
Low
Shionogi Japan
(Iwate, Shiga, Osaka, Hyogo)
5 4 1
Shionogi Pharma Chemicals Japan
(Tokushima)
1 1
C&O Nanjing Plant China
(Jiangsu)
1 1

Self-assessment

Water risk category Risks and opportunities Financial impact Probability of occurrence Remarks
Physical risk Water shortage Discontinued operation due to droughts Large (discontinued operation) Low Has not occurred in at least the last 30 years
Water excess Discontinued operation due to floods Large (discontinued operation) Low Has not occurred in at least the last 30 years
Water quality deterioration Site operation suspended due to water quality deterioration Large (discontinued operation) Low Has not occurred in at least the last 30 years
Regulatory risk Additional investment in waste water treatment following reinforced waste water quality criteria Medium (capital investment) Intermediate Respond to applicable administrative policies in all sincerity
Reputation risk Compromised public confidence due to environmental pollution by waste water from the site Large (compromised confidence) Low Recovering public confidence is difficult; must focus effort on this risk item

Water consumption

To protect water, the Shionogi Group keeps accurate measures of its water consumption, both tap water and industrial water, and strives to conserve water by reviewing its manufacturing equipment operation and cleansing methods. We obtain the water we use entirely from the public water supply system, with no direct water intake from underground, rivers or the sea. We release waste water into sewers or rivers, not into the sea. Our waste water, purified by in-house treatment facilities and constantly monitored for any abnormality, conform to our management criteria, which are voluntarily set more stringently than those mandated by laws and regulations. The quantity of actual water consumption by the operating sites corresponds to about 10% of the quantity of water taken in, since a large part of the water used for our activities is returned to the aquatic environment.
Water consumption and productivity (1,000 m3) [FY2014] Water consumption: 1,583, Sales/water consumption: 173 [FY2015] Water consumption: 1,567, Sales/water consumption: 198 [FY2016] Water consumption: 1,528, Sales/water consumption: 222 [FY2017] Water consumption: 1,389, Sales/water consumption: 248 [FY2018] Water consumption: 1,315, Sales/water consumption: 277
Water consumption by source (1,000 m3) [FY2014] Tap water: 332, Industrial water: 1,251, Underground water: 1 [FY2015] Tap water: 303, Industrial water: 1,264, Underground water: 0 [FY2016] Tap water: 289, Industrial water: 1,239, Underground water: 0 [FY2017] Tap water: 280, Industrial water: 1,109, Underground water: 0 [FY2018] Tap water: 254, Industrial water: 1,061, Underground water: 0
Drainage by destination (1,000 m3) [FY2014] Sewers: 433, Public waters: 1,021 [FY2015] Sewers: 348, Public waters: 985 [FY2016] Sewers: 335, Public waters: 998 [FY2017] Sewers: 340, Public waters: 900 [FY2018] Sewers: 310, Public waters: 864

Environmental impact assessment of pharmaceutical ingredients contained in waste water

In the facilities where antimicrobials are produced, we first deactivate antimicrobials contained in waste water and release it into in-house waste water treatment facilities, confirming that the level of antimicrobial content is void of environmental threat if the waste water is released into the environment. With regard to substances other than antimicrobials, at the outset of manufacturing each new product, we confirm that its pharmaceutical ingredients contained in treated wastewater do not have any impact on the natural environment.
[Testing the activity of an antimicrobial] Left: Before inactivation (inhibition circle formed) / Right: After inactivation (inhibition circle not formed)