Notice Regarding the Status (Progress Report) of Acquisition of Own Shares
(Acquisition of own shares pursuant to the provision of Article 165, Paragraph 2 of the Companies Act)

Osaka, Japan, January 8, 2021 - Shionogi & Co., Ltd. (Head Office: Osaka; President & CEO: Isao Teshirogi, Ph.D.; hereafter “Shionogi”) today announces that it has acquired its own shares pursuant to the provisions of Article 156 of the Companies Act, applied by replacing terms pursuant to the provisions of Article 165, paragraph 3 of the same Act. The status (progress report) of the acquisition is as follows.

1.        Class of shares acquired                            Common stock of the Company

2.        Total number of shares acquired               1,777,800 shares

3.        Total value of shares acquired                 9,941,835,798 yen

4.        Period of acquisition   

          From December 1, 2020 to December 31, 2020 (execution base)

5.        Method of acquisition   

          Acquire in the open market through discretionary trading in Tokyo Stock   Exchange

(Reference)

1.       Details of the resolution at the meeting of the Board of Directors held on October 30, 2020

   (1)     Class of shares to be acquired                   Common stock of the Company

   (2)     Total number of shares to be acquired      9,500,000 shares (maximum)

                             (3.1% of total outstanding shares [excluding treasury stock])

   (3)     Total amount of acquisition cost               50 billion yen (maximum)

   (4)     Period of acquisition                                  From November 1, 2020 to March 31, 2021

2.      The accumulative number and value of own shares acquired pursuant to the resolution above (on December 31, 2020)

   (1)     Total number of shares acquired               3,650,200 shares

   (2)     Total value of shares acquired                   20,437,735,994 yen