Release
2023/06/19
OSAKA, Japan, June 19, 2023 - Shionogi & Co., Ltd. (Head Office: Osaka, Japan; Chief Executive Officer: Isao Teshirogi, Ph.D.; hereafter "Shionogi") and KOTAI Biotechnologies, Inc. (Head Office: Osaka, Japan; Chief Executive Officer: Kazuo Yamashita, Ph.D.; hereafter "KOTAI") announced meeting the criteria set in advance for the companies’ joint research effort to create a Universal Sarbecovirus1 Vaccine that can induce neutralizing antibodies against a wide range of sarbecovirus strains and variants.
The Universal Sarbecovirus Vaccine antigen is designed to selectively induce neutralizing antibodies against regions where viral mutations are unlikely to occur and which are conserved across coronaviruses. This vaccine is expected to help to prepare for future potential COVID-19(SARS-CoV-2) mutant variants and potential new coronavirus pandemics, avoiding the need to continually develop new vaccines against continually evolving and emerging coronavirus mutant variants.
Under the terms of the collaboration agreement, KOTAI will receive a milestone from Shionogi for the identification of an antigen meeting the predefined success criteria for the ability to induce neutralizing antibodies across a breadth of coronavirus virus variants and strains. This collaboration has been funded and included2 in the vaccine / new modality research and development project, as part of a public solicitation by SCARDAa established within AMEDb.
Shionogi and KOTAI will continue to progress the research and development of a Universal Sarbecovirus Vaccine, with the support of SCARDA, to seek to bring this important advancement to patients around the world rapidly, through the synergistic combination of Shionogi’s expertise in infectious diseases with KOTAI’s capabilities in the analysis of immunity and protein structure using information technology.
1. SARS-CoV-2 and SARS coronavirus belong to the subgenus Sarbecovirus.
2. June 30, 2022 Press Release
a. SCARDA : Strategic Center of Biomedical Advanced Vaccine Research and Development for Preparedness and Response
b. AMED : Japan Agency for Medical Research and Development
【About SCARDA】
SCARDA is an organization established within the Japan Agency for Medical Research and Development (AMED) in March 2022. Based on the "Vaccine Development / Production System Strengthening Strategy" decided by the Cabinet in June 2021, it was organized for the purpose of strengthening the R&D / production system during normal times so it will be ready in times of pandemic emergency. AMED boosts the funding capacity for strategically significant research, initiative for world-leading vaccine research and development centers and promotes the strengthening of the pharmaceutical startup ecosystem. Please see SCARDA website for details.
【About KOTAI】
KOTAI is a biotechnology company established in 2016 based on research results from Osaka University. As a group of experts in the information analysis of immunity and protein structure, KOTAI conducts research and development in collaboration with many research institutes, universities and pharmaceutical companies. Please see the KOTAI website for details.
【About Shionogi】
Shionogi is committed to the principle “Protecting people worldwide from the threat of infectious diseases” as our key focus, and is working on the realization of total care for infectious diseases. While contributing to the safety and security of society, we will be prepared for the swift provision of therapeutic drugs and vaccines as necessary depending on the situation, such as the emergence of new variants or the future prevalence of the disease. Please see SHIONOGI website for details.
For Further Information, Contact:
SHIONOGI Website Inquiry Form : https://www.shionogi.com/global/en/contact.html